Saturday, February 19, 2011

Ceftizoxime

Ceftizoxime
Systematic (IUPAC) name
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-
2-methoxyiminoacetyl]amino]-8-oxo-5-thia-
1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Identifiers
CAS number 68401-81-0 68401-82-1 (sodium salt)
ATC code J01DD07
PubChem CID 6533629
KEGG D07658
Chemical data
Formula C13H13N5O5S2 
Mol. mass 383.405 g/mol
Therapeutic considerations
Pregnancy cat.  ?
Legal status  ?
Ceftizoxime is a parenteral third-generation cephalosporin. Unlike other 3rd generation cephalosporins , in ceftizoxime the whole C-3 side chain has been removed to prevent deactivation by hydrolytic enzymes . It rather resembles Cefotaxime in its properties , however not being subjected to metabolism .

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