Cefixime

Cefixime

Systematic (IUPAC) name
(6R,7R)-7-{[2-(2-amino-1,3-thiazol-4-yl)-2-(carboxy methoxyimino)acetyl]amino}-3-ethenyl-8-oxo-5-thia- 1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Identifiers
CAS number	79350-37-1
ATC code	J01DD08
PubChem	CID 5362065
DrugBank	APRD00583
ChemSpider	4514923 Y
UNII	97I1C92E55 Y
KEGG	D00258 Y
ChEMBL	CHEMBL1541 Y
Chemical data
Formula	C16H15N5O7S2
Mol. mass	453.452 g/mol
SMILES	eMolecules & PubChem
InChI[show] InChI=1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/b20-9-/t10-,14-/m1/s1 Y Key: OKBVVJOGVLARMR-QSWIMTSFSA-N Y
Pharmacokinetic data
Bioavailability	40% to 50%
Protein binding	Approximately 60%
Half-life	Variable Average 3 to 4 hours
Excretion	Renal and biliary
Therapeutic considerations
Pregnancy cat.	B
Legal status	?
Routes	Oral
Y(what is this?)  (verify)

Cefixime is an oral third generation cephalosporin antibiotic. It is used to treat gonorrhea,^[1] tonsilitis,^[2] and pharyngitis.^[2]
The usual dose is 400 mg in two divided doses for up to 5-7 days.
It was sold under the trade name Suprax in the USA, until 2003 when it was taken off the market by drug manufacturer Wyeth after its patent expired. The oral suspension form of "Suprax" was re-launched by Lupin in the USA.

Posted in: